Our Housebets picks of the week are here again as we get set for another round of top football action across Europe’s domestic leagues.
European football clubs turn their attention to domestic action this weekend, following the conclusion of the Champions League and Europa League league stage phase.
The Champions League and Europa League games delivered unending excitement right up to the last minute, and fans will hope it carries over to the weekend round of games across different leagues.
This weekend promises to be exciting, with a host of top football games to look out for across each league. In England, Manchester United will hope to make it three wins in a row when they host Fulham.
Meanwhile, in Italy, Inter Milan will be looking to strengthen their grip at the top of Serie A when they take on Cremonese on Sunday.
As usual, you can place your bets on all of the games and other events at Housebets, including the Australian Open final.
While there are many games to look forward to this weekend, we have carefully selected our picks from the football fixtures across Europe’s top leagues. You can place your bets on these games and other matches at Housebets.
All you need to do is log in to your account or create one if you don't already have one, deposit your preferred cryptocurrency and go to the sports section to bet on these picks.
With that said, let us jump straight into our picks of the week.
Our Pick: Chelsea win or Over 2.5
Chelsea are back in Premier League action, as they host London rivals, West Ham, at Stamford Bridge on Saturday afternoon.
The Blues have been on a good run of form recently, winning their last three games in all competitions, including the superb win over Napoli in the Champions League during the week.
Chelsea went into that game needing to win to automatically finish in the top eight, and they did just that.
Liam Rosenior’s men had to come back from 2-1 down to win 3-2, showing that the players are ready to fight for the former Strasbourg manager.
Rosenior will now hope that his side can keep up the momentum when they host the Hammers on Saturday.
Chelsea will approach the match full of confidence, as they have won their last four Premier League games against West Ham by an aggregate score of 15-2.
The Blues have dominated this fixture in recent years, winning seven out of the last ten and losing just twice.
However, they face a Hammers side that has enjoyed a little bit of resurgence in recent matches. The Hammers may be fighting relegation, but they have won their last three games in all competitions, including two in the Premier League.
The bad news, however, for West Ham is that they have not won a league game at Stamford Bridge since the 2019/2020 season.
They did manage to give Chelsea a hard battle last time out at the Bridge, but the Blues came back from a goal down to win 2-1.
A similar outcome is expected, with Chelsea currently priced at 1.57 to win. West Ham, meanwhile, are priced at 5.80 to get a rare away win at the Bridge.
However, considering there have been 17 goals scored in the last four meetings between the two, over 2.5 goals at 1.54 could also be another option.
Our Pick: Over 2.5 goals
Liverpool and Newcastle will face each other at Anfield on Saturday night, following their Champions League exertions during the week.
While Liverpool made light work of Qarabaq with a 6-0 win at Anfield, Newcastle had to battle hard for a point against defending champions Paris Saint-Germain at Parc des Princes.
The result meant the Reds qualified for the round of 16, while Newcastle will have to navigate the playoff rounds.
But before the knockout stages, they have a score to settle on Saturday. In Liverpool’s case, they will be looking for their first league win since the turn of the year.
The Reds lost to Bournemouth last weekend and drew their previous four prior to that defeat to the Cherries, meaning they have not won any of their five league games in 2025.
Arne Slot’s men will hope to put an end to that on Saturday, though, as not since 1954 have Liverpool failed to win their first six league games of a calendar year.
The Reds do stand a good chance of winning on Saturday, as they are unbeaten in their last ten league meetings against Newcastle (8W 2D). Slot’s men also won the reverse fixture, with Rio Ngumoha scoring an injury-time winner to inflict an agonising 3-2 defeat against Eddie Howe’s men.
Newcastle will be seeking revenge for that defeat, but they lost 2-0 at home to Aston Villa last weekend. The Magpies have, however, won three of their last four league games and also earned a respectable point against PSG on Wednesday.
However, despite Newcastle’s impressive fighting spirit, Anfield has always been a difficult ground for them.
They have not won a league game at Anfield in over 30 years and are winless in their last 29 away league games against Liverpool.
Nonetheless, Saturday could be the perfect time for Newcastle to end their winless run at Anfield. The Magpies are priced at 3.95 to get the win, while Liverpool are backed at 1.79 to get their first league win of the year.
However, over 2.5 goals at 1.60 could be the safest option, considering this is the fifth-highest scoring fixture in Premier League history.
Our Pick: Marseille to win either half
Football can be cruel; just ask Olympique Marseille players and coaches. The Phocaeans were just seconds away from qualifying for the Champions League playoff rounds on Wednesday but missed out after Anatoliy Trubin’s header sealed a Benfica 4-2 win over Real Madrid.
Marseille were in the final spot after losing 3-0 to Club Brugge, but Trubin’s goal meant Benfica overtook them on goal difference.
It was a cruel way to crash out, but Marseille cannot dwell on it too much because they have another huge Ligue 1 clash against Paris FC on Saturday.
Roberto De Zerbi’s men picked up their first league win of the year last weekend, courtesy of a 3-0 win over title rivals RC Lens.
The win was much needed after a disappointing start to the year. However, they need to continue in the same vein against Paris, especially after their exit from the Champions League.
It will be a difficult game for De Zerbi’s men, though, as they face a Paris side unbeaten in their last two league games.
While they have failed to score in their last two games, they have also kept a clean sheet, showing the work that Stephane Gilli has done to make Paris a harder side to beat.
However, despite their recent form, the Parisians are winless in their last six league games at home, which should give Marseille some sort of confidence.
The Phocaeans are the favourites and have been priced at 1.88 for a win. However, backing them at 1.45 to win either half may be a safer option.
Our pick: Over 2.5 goals
It has been a torrid week for Eintracht Frankfurt after they were knocked out of the Champions League, having suffered a disappointing 3-1 defeat to Hoffenheim last weekend.
The Eagles are also without a permanent coach after Dino Toppmoller was dismissed following a poor run of results. Frankfurt are winless in their last seven fixtures in all competitions and have only won one of their last 12.
However, the positive for Frankfurt is that they are clinical in front of goal. They have scored nine goals in their last nine league games and are the third highest-scoring team in the German top flight this season.
While their attacking display is something to admire, their defence has been the opposite. The Eagles have conceded at least two goals in their last seven games.
It does not get easier as they face a Leverkusen that beat Villarreal 3-0 in the Champions League and defeated Werder Bremen 1-0 last weekend.
However, Leverkusen have not really been convincing themselves, having won three and lost three of their last six league games.
The Factory XI do have an impressive record against Frankfurt, though, having won the last six league meetings between the two sides. But despite their impressive record against the Eagles, it is hard to predict the winner here.
Kasper Hjulmand’s men are priced at 2.22 to win, while Frankfurt are priced at 2.88 to get their second home win in just eight games.
Over 2.5 goals at 1.55 seems to be the safest option here, however.
Our Pick: Napoli Win
Antonio Conte’s struggles in Europe were on full display yet again after Napoli crashed out of the Champions League following a 3-2 loss to Chelsea.
Conte has always struggled to crack European competitions, and Wednesday’s result only added to his misery.
However, there is no time to dwell on what could have been, as Napoli have a huge Serie A game at home against Fiorentina.
Having lost 3-0 to Juventus last weekend, it is important for Napoli to win this weekend if they are serious about defending their title.
The Neapolitans are already nine points behind Inter Milan and are only one point ahead of Juventus in fifth place, meaning they might not only defend their title, but they might also miss out on Champions League qualification.
There should be no problem winning Saturday’s game, though, as they face a Fiorentina side coming into the game on the back of a 2-1 home loss to Cagliari.
La Viola have been the most disappointing Serie A side this season, sitting in 18th place, one point behind safety. They are also winless in their last five games against the side from Naples.
Fiorentina are the underdog in this game, as they are priced at 5.40 to get the win. However, a win for Napoli looks like the safest option, and you can back Conte’s men at 1.74.
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NB: *Odds are subject to change. Odds accurate as of 29-01-2026 23:00 CET. Also, this is not financial advice
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